At present, practices of Humanistic Buddhism are widely accepted by many Buddhist devotees. Thus, it has become the mainstream in contemporary Buddhist faith. Looking back, the Life Buddhism advocated by Master Taixu established the basic conceptual framework for the theoretical system of Humanistic Buddhism of his disciple, Master Yinshun. This paper attempts to explore the following questions: • The Buddhist modern revitalization, in response to the secularization and vulgarization, aimed to set Buddhism in the right direction and prevent its deterioration. Why did it take Master Taixu’s Life Buddhism and its later development, Humanistic Buddhism, to actualize the aims of the Buddhist modern revitalization? • How did the Buddhist reform movement synchronize and adapt with the vicissitudes of the times in the late Qing Dynasty and early days of the Republic of China? • What is the vital life experience of Master Taixu that led him to take on the mission of establishing Life Buddhism? The answers to these questions should be valuable references for deeper understanding and grasping the meaning of Humanistic Buddhism accurately, as well as reflecting on the advantages and disadvantages of contemporary Humanistic Buddhism