Mathematics performance in all subject areas plays an important role. Some students in mathematics performance is not satisfactory, most mathematics achievement performance is relative to emotional factors, and mathematical anxiety is the most important one. When mathematics learning, math anxiety students worry variety of mathematically related factors, worry will effects on cognitive resources, and reduce processing math homework working memory capacity, then influence mathematics performance. In recent years, the rise of the concept is mindfulness, the important mechanisms are self-regulation and working memory performance upgrade. The research wants to discuss the relevance of mindfulness and physical and mental state of the country carried out in stages for teenagers, then through mindfulness intervention to improve individual focus on mathematics learning and reduce anxiety, hoping to enhance the mathematical working memory functioning and academic performance. We proposed three studies: First, we are trying to explore the association between mental health and mindfulness by measuring the mindful awareness attention scale, Satisfaction with Life Scale, Center for Epidemiological Studies Depression Scale, Inventory of Adolescent Resilience, and the Positive and Negative Affect Schedule. Second, controlling the Big-Five factors, analying the mediation process of Digit Span to investigate the prediction of mindfulness to mathematics performance. Third, exploring if the mindfulness practice during class can benefit the math performance, working memory, and mental health. On the whole, we have confirmed the adaptability of Chinese Translation of Mindful Attention Awareness Scale on adolescence stage, and the connection between mindfulness and mathematics. Otherwise, under the premise of phonological digi span task, the importance of current message stimulated by attention received and phonological loop processed are greater than the working memory in the central control system for attention to the conversion and suppression processing. In the aspect of three minutes mindfulness practice intervention, there having no obvious effect in reducting mathematical anxiety and the improvement of phonological loop ability in working memory, but there is indeed a substantial help for the students to show the results of mathematics, we have confirmed that the three-minute mindfulness exercise is a popular approach and does not require a special degree of readiness to improve the learning ability of the adolescence. It can be a reference for teacher when practicing in the educational field.