The research topic of this study focuses on the “middle way” thinking in the Buddhist classic - Sutra of the Great Virtue of Wisdom, as well as on finding out its connection with the “middle way” thinking mentioned in Nagarjuna’s Mūlamadhyamakakārikā (Fundamental Verses on the Middle Way) translated by Kumārajīva, in an attempt to prove that there indeed is a connection between them and verify that the thinking of “middle way” exists in Sutra of the Great Virtue of Wisdom. The “middle way” thinking in Nagarjuna’s Mūlamadhyamakakārikā (Fundamental Verses on the Middle Way) was also developed from the perception of meanings in relevant original Buddhist classics. In addition, this study also intends to conduct textual research and confirms that the interpretations and explanations of meanings of words about “middle way” in the Buddhist texts translated by Kumārajīva are originated from his translation of Sutra of the Great Virtue of Wisdom. This study includes a total of 7 chapters to perform investigations, which are briefly described as follows: Chapter 1 is divided into 4 sections to outline the author’s summary of the research topic and the research scope & objectives, as well as to describe in detail the research motives and methods to enable readers to have a preliminary understanding of this study and further understand the author’s research process. Chapter 2 is divided into 2 sections to outline the core Buddhist classics in this study, and to review relevant research results in academia. The content outlines the original Buddhist classics, such as Prajñāpāramitā (The Perfection of (Transcendent) Wisdom), Mahāprajñāpāramitāśāstra (Great Treatise on the Perfection of Wisdom), and Mūlamadhyamakakārikā (Fundamental Verses on the Middle Way), and tabulates and classifies in detail the core basis, the important Buddhist classic - Sutra of the Great Virtue of Wisdom. The research focuses on the “middle way” thinking are introduced, and the research scope is defined to enable readers to further understand the chapters of Buddhist texts investigated in this study. Afterwards, this study classifies academic studies, and outlines the studies concerning Wisdom in Buddhism, “middle way” thinking, Kumārajīva, and Mūlamadhyamakakārikā (Fundamental Verses on the Middle Way). This study also chooses one article from them, respective, for investigation, in order to enhance and explicitly present the key concepts of this study. Chapter 3 is divided into 3 sections to investigate the development of “middle way” thinking in Buddhism according to the specific books, such as Middle Way and Bodhi-Path in Āgama, Introduction to Madhyamaka Thinking, and Bu