In this article, two major themes will be discussed through Zhang-zai’s view point of life and death, which are to understand the natural trend of death and to search the meaning of life. Based on the themes showed above, the main points in this article will be discussed through four steps showed as below. First, to clarify how Zhang-zai explained the natural trend of death through his Qi theme, “Qi theme and the phenomenon of life and death” arranged in the second section of this article. Second, to point out how Zhang -zai concluded his attitude to death as another type of life but the end of life, “Zhang-zai’s thoughts to death” arranged in the third section. Third, to elucidate how Zhang-zai explained the meaning of life through his Si-wei theme, “Zhang-zai’s search for the meaning of life” arranged in the fourth section. Last, in the fifth section “Transforming One's Physical Nature and A Life Education”, we will indicate how Zhang-zai expounded the possibility of “Moral Cultivation” through the way of “Transforming One's Physical Nature.”