This paper traces the origins of the decorative honeysuckle patterns in early Mogao caves along two lines of investigation. The first traces the Western influences evident in the patterns, namely the artistic styles of ancient Mesopotamia, ancient Greece, and Gandhara. The second line of investigation focuses on the Eastern influences behind the pattern, including traditional Chinese plastic arts from the pre-Qin and Han dynasties and the artistic styles of central China during the Northern and Southern dynasties. Tracing the historical development and cultural influences that produced the honeysuckle patterns grants a comprehensive view of both the uniquely regional artistic characteristics and the globally aware aesthetic consciousness of Dunhuang art.