The implication of religious globalization is not merely about spreading one's doctrines worldwide or ensuring followers in every region of the globe. Religions must focus on global issues, integrating religious values with universal values to collaboratively solve global problems. Religious globalization is inevitably related to the universality of religion, meaning that religion can enter various worldly domains to solve a variety of issues while avoiding severe conflicts with other ideologies. This is undoubtedly a significant challenge. Tzu Chi has created a new model in the process of globalization, which is to act with compassion and altruism, allowing different religions to collaborate on a platform of great love and common goodness, offering solutions to global human problems. At the same time, the collaborative model represented by Tzu Chi with global non-profit organizations and government departments is also a practice of the concept of harmony. This corresponds to the Western theory of collaboration, which advocates that large, medium, and small enterprises, public and private sectors, and institutions and organizations at both vertical and horizontal levels across countries need to collaborate to address the increasingly complex problems of today's world. Through collaborative mechanisms, individual religions, organizations, and governments work together on three major issues facing humanity: First, environmental sustainability; second, the disparity between the rich and the poor; and third, the impact on human ethics and life brought about by the advent of the knowledge economy. Tzu Chi's altruistic and harmonious model has transcended religious, racial, cultural, and national barriers, becoming a very important paradigm in today's discourse on globalization. Therefore, based on Buddhist compassion and altruism, using harmony as the method, and applying the model of common good to various fields, promoting a good economy, good governance, good communication, and a good environment, etc., establishing a human civilization of goodness seems feasible and necessary. The essence of goodness is "altruism" and "harmony," establishing a global civilization motivated by altruism, methodized by harmony, and aimed at common goodness.