The study aims to discuss the activities of Shinshū Otani-ha activities of Japanese Jōdo Shinshū Otani-ha (Higashi Honganji) between the Cross- straits during the Meiji era (1873~1912). Shinshū Otani-ha is considered as the beginning of Japanese Buddhism activities in China, with Ogurusukoucyou (1831~1905) as its exponent. Since Buddhism was prohibited and destroyed during the Meiji era, Shinshū Otani-ha extended its missionary activities in China for survival and development. Initially, the missionaries aimed at helping Japan and China oppose western religions. However, they lost their original purpose and sought to expand overseas due to national interest. In the Jiawu War, Japan colonized Taiwan in order to invade South China. During the 31st year of the Meiji era (1898), Shinshū Otani-ha sent monks from either Japan or the missionary organizations in Taiwan to Fujian province. This was also carried out earlier in Taiwan. As an excuse for Japan to invade and take control of Fujian province, Takamatsusei, the priest of Higashi Honganji burned himself in Xiamen Higashi Honganji during the the Yihetuan Rebellion in the 33rd year of the Meiji period (1900). Despite the changes in its activities between the Cross-straits due to historical influences, Shinshū Otani-ha remained an accomplice of the Japanese Empire.